Bio Spot Defense Flea & Tick Review


Fleas are disgusting. Pet owners want to avoid them on their pet and in their house, but it’s easier said than done.

This is where pharmaceutical manufacturers and distributers come in – they help you manage fleas, ticks, lice, and other worms easily with different treatment methods.

How do you know which treatment is the best for your pet? Of course, there are tons of great options in the market to choose from and there are hundreds of reviews for almost every product, making it easier for you to weigh the pros and cons of each.

Let’s dissect how Bio Spot Defense Flea and Tick works.

Company claims

The Bio Spot Defense Flea and Tick for dogs and cats claims to make it easier for pet owners to apply the treatment to pet fur to avoid spillage and allow for easy application. It comes with a Smart Shield Applicator that is specifically designed to help pet owners with treatment application without getting it on their hands or clothes.

Bio Spot Defense Flea and Tick kills all stages of fleas, ticks, and also protects against mosquitoes.

Here’s a detailed list of what you can use this treatment for –

  • Fleas
  • Ticks
  • Mosquitoes
  • Flea and tick eggs
  • Larvae

The treatment starts killing fleas and ticks within 15 minutes of application and protects your pets against re-infestation for up to 75 days.

How it works

Bio Spot Defense Flea and Tick treatment works by killing fleas, ticks, and mosquitoes. It has the following active ingredients:

  • Etofenprox
  • (S)-methoprene
  • Piperonyl botuxide
  • Other undisclosed ingredients

The quantity of ingredients varies depending on the type of dosage chosen for a specific type of pet.

Etofenprox is a pyrethroid that is harmless to humans and is environment friendly. It acts by opening sodium channels in neuronal membranes causing paralysis and death.

Etofenprox is always combined with piperonyl botuxide, which is an organic compound. It allows pyrethroid to remain in the animal for a longer time.

(S)-methoprene acts as a growth inhibitor to prevent larvae and eggs from becoming adults.

Usage information

Bio Spot Defense Flea and Tick is a waterproof treatment that should be applied once a month for three months. It is available for cats and dogs. Dosages vary for each species and are also dependent on the size of the pet.

The treatment is available online through multiple retailers and also over the counter at pet stores.

Bio Spot Defense Flea and Tick Spot On for Cats should only be used on cats that are 12 weeks or older, while Bio Spot Defense Flea and Tick Spot On for Dogs should be used on dogs that are over 6 months old.

There’s no information available on the use of Bio Spot Defense Flea and Tick for pregnant or breeding animals. Please consult your vet before use.

Product warnings and side effects

Take caution while applying the treatment. It comes with an applicator which limits human contact with the treatment, limiting any side effects. However, it is a known eye irritant.

Manufacturers of the Bio Spot Defense Flea and Tick recommend that you should wash your hands and face after applying the treatment on your pet.

It may trigger skin sensitivities in some pets such as itching, inflammation of skin, and even hair loss.


Pet owners are definitely divided on this one. Most pet owners have mentioned that the Smart Shield Applicator is difficult to use and results in excessive treatment deposits on pet skin. Whether or not it works seems to be about equally divided.

We say that there are probably better spot ons out there. Click here to find some that we recommend.

If you’ve used this product before, please share your experience with us in the comments section below.

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