Warning: session_start(): open(/var/lib/php/sessions/sess_lf48s5bj6t2gnech81bkqj9u76, O_RDWR) failed: No space left on device (28) in /home/forge/fixfleas.com/public/wp-content/plugins/wp-custom-admin-bar/custom-admin-bar-functions.php on line 8

Warning: session_start(): Failed to read session data: files (path: /var/lib/php/sessions) in /home/forge/fixfleas.com/public/wp-content/plugins/wp-custom-admin-bar/custom-admin-bar-functions.php on line 8
Advantix II Vs Advantage II for Dogs and Cats

Advantix II Vs Advantage II


Which Flea Drop is Best for Your Pet?

If you’ve been to your local pet store lately in an attempt to find a good flea drop, you were probably astounded at the number of products available.

The prices vary as much as the name, but relax. We’re going to help you find the flea control pill that’s right for you. Today we’re going to compare Advantix II vs Advantage II to help you get started.

What Do They Do?

Both Advantage II and Advantix II are over the counter flea drops that claim to kill fleas on dogs and cats.

Advantage II has two active ingredients: Imidacloprid, a neurotoxin that kills adult fleas, and pyriproxyfen, an insect growth inhibitor that kills flea larvae and eggs. It’s effective against fleas, flea larvae and lice and is safe to use in puppies 7 weeks and older and kittens 8 weeks and older.

Advantix II actually has three active ingredients: imidacloprid and pyriproxyfen just like Advantage II, but also permethrin. It kills and repels fleas, ticks, and mosquitos, repels biting flies and kills lice. Advantix II is only for use on dogs.

Side Effects and Warnings

The most common side effect of both flea drops is irritation at the application site. This should go away within a couple of days. More severe, but much more rare, side effects include:

  • Lethargy
  • Hyperactivity
  • Drooling
  • Shaking
  • Poor Coordination
  • Excess vocalization
  • Hives or red skin
  • Hair loss at application site

If your pet exhibits any of these side effects, wash the area with dishwashing liquid and contact your vet immediately.

It’s also important that you know that permethrin, one of the ingredients in Advantix II, is toxic to cats so if you’re using it in a household with felines, you need to keep your dog separated until it’s completely dry.


There are two notable differences between these products that relate to the same ingredient.

  1. Advantix II has permethrin that makes it a broader-acting pesticide
  2. Permethrin is toxic to cats. If you’re looking for a cat product, Advantage II is perfect but stay away from Advantix.

If you’ve used either Advantage II or Advantix II, or both, please tell us about your experience in the comments section below.

Be the first! Share your experience!

Tell Us What You Think!

Spam protection (register to skip this)

Time limit is exhausted. Please reload the CAPTCHA.