Advantage II for Dogs Review

Looking for a Safe Spot-On Flea Treatment?


Choosing the right flea product for your dog is difficult for most people because the only information available is what is posted by the company.

We’re going to find out whether or not Advantage II is a good product for dogs based upon the active ingredients, user reviews and common sense.

Company Claims

This product is a topical insecticide that kills adult fleas and prevents the eggs from hatching. It only has to be applied once a month and gives full protection for the entire 30 days.

It will also control lice but does not prevent ticks from embedding in your dog’s skin. If you are in an area with a high number of ticks, then you may want to use a second product to prevent tick bites.

It is waterproof and does not have to be reapplied after your dog has a bath or plays outside in the rain. You do have to avoid water for 24 hours after application, to give the medicine time to coat your dog’s skin.

Active Ingredients

The two active ingredients for Advantage II for Dogs are:

  • Imidacloprid
  • Pyriproxyfen

How Does Advantage II Work?

Imidacloprid acts as a neurotoxin that leads to paralysis and eventual death in fleas. It is also slightly toxic to mammals and should only be used on the outside of your dog. It is one of the most widely used insecticides in the world but it is considered moderately toxic when ingested orally.

Pyriproxyfen is a juvenile hormone analog that prevents insect pupa from developing into adults. It interrupts the life cycle of the fleas by preventing the full development of the insect. It is completely non-toxic to humans and has been shown to have no detrimental effect on other mammals.

Usage Information

Advantage II for Dogs should be applied to the skin at the base of the neck. If you have a large dog, you may want to divide the treatments in different areas to insure an even coating. You want to avoid washing your dog for 24 hours and you want to keep the medicine away from the eyes and mouth.


There are several concerns regarding the use of this product by people who also have small children. This is because the warning on the package says it can be harmful if ingested and you should avoid exposure to skin. Small children may mistakenly pet the animal and put their hands in their mouth. This has caused many users to switch to a different product but in reality, you shouldn’t let your kids touch any pesticide.

There have also been reports of people getting the medicine on their hands and having irritation for 24 to 48 hours. This has caused some concern because if it has this reaction on human skin, how does it feel for the dog.

Side Effects and Precautions

The side effects of this spot-on treatment, if used correctly, are normally minor. There may be a slight rash on the skin around the treated area, but the normally disappears within one or two days.

It does have a warning that it is harmful if ingested and you should call a poison control center if you accidentally get any of the Advantage in your mouth.


Based upon the customer reviews, we recommend Advantage II for Dogs. As long as you’re only looking for a flea preventative. If you live in an area that has ticks, you may want to try something else.

Click here to find a great deal on Advantage II for Dogs.

If you’ve tried Advantage II for dogs, please tell us about your experience in the comments section below.

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