Trifexis Vs Comfortis
Which Flea Tab is Right for You
Trying to decide which flea control product to use is difficult, especially with so many different options on the table.
Today we’re going to take a look at two of the top chewable flea control pills, Trifexis and Comfortis, and explain the difference between the two so that you’ll know which one is right for you.
We’ll start with what they can do, then move on to safety issues.
What Do They Do?
Comfortis and Trifexis share one common ingredient, Spinosad. This is an ingredient used in several of the leading flea treatments and kills fleas within 4 hours of administration. Unlike other oral flea meds, Spinosad continues to kill fleas for up to 30 days.
Also unlike many other flea killers, Spinosad only kills adult fleas; it doesn’t kill eggs or larvae and it doesn’t repel them.
Spinosad is the only ingredient in Comfortis so adult fleas are all that it is effective against. That’s fine, if that’s all that you need. Trifexis, on the other hand, has milbemycin oxime in addition to Spinosad.
Milbemycin oxime is a common ingredient used to prevent heartworms and intestinal parasites such as adult roundworms, adult whipworms and hookworms. It prevents heartworms by killing the juvenile worms in the bloodstream before they reach the heart.
Comfortis is safe to use on cats, kittens, dogs and puppies 14 weeks of age and older. Dogs have to be at least 3.3 pounds and cats need to be at least 2 pounds.
Side effects of Spinosad (the one in both Comfortis and Trifexis) are rare and include vomiting, hyperactivity, lethargy, increased appetite, diarrhea, drooling, excess vocalization, hives, and skin irritation.
Side effects of milbemycin oxime, the ingredient used for heartworms and intestinal parasites, include depression, drowsiness, nausea, skin irritation, drooling, diarrhea, loss of appetite and seizures. These are extremely rare as long as your dog doesn’t have heartworms when you give him the pill.
The bottom line is that both Comfortis and Trifexis contain Spinosad to kill the fleas that are on your dog, and keep them dead for 30 days. The determining factor for you is going to be whether you want to also treat for heartworms and intestinal worms. If so, then you’ll want to use Trifexis. Both pills are available only from your vet, so talk to him about it if you have more questions.
If you’ve tried Comfortis or Trifexis, or even better, both, let us know about your experience in the comments section below.