Advantage II Side Effects

Better than the Original, or Still a Dud?


Are you trying to find a flea drop treatment that really works?

We’re going to take a look at Advantage II to see if it may be the spot-on treatment that will work for you.

How Does Advantage II Work?

There are two active ingredients in Advantage II. The first, imidacloprid (9.1%), is a neurotoxin that causes paralysis and death in the adult fleas. The second, pyriproxyfen (0.46%), is an insect growth regulator, or IGR. It keeps the flea eggs from hatching so that you don’t have a vicious cycle of re-infestation.

It comes in different doses based upon the weight of the dog.

What are Advantage II Side Effects?

The primary side effect of Advantage II is irritation at the site of administration. This should go away within a day or two but if it doesn’t, or if your pet is extremely disturbed by it, give him a bath in warm water to remove it> Call your vet if it doesn’t get better or if you pet exhibits any of the less common side effects listed below.

Though extremely rare with this product, side effects are possible and include:

  • lethargy
  • Hyperactivity
  • Drooling
  • Shaking
  • Poor Coordination
  • Excess vocalization
  • Hives or red skin
  • Hair loss at application site

Final Word

Advantage II has a high rate of user satisfaction and very few instances of side effects or allergic reactions. For these reasons, we feel comfortable giving a thumbs up to this flea drop. If you do happen to notice any odd behavior that you may believe to be a reaction, bathe your dog and call your vet immediately.

To save time and money, click here to find great deals on Advantage II online.

If you’ve tried Advantage II on your pet, please tell us about your experience in the comments section below.

3 Responses to “Advantage II Side Effects”
  1. Patricia says:

    The original Advantage was much better.Advantage 11 does not kill all fleas on dogs or cats Is it at all possible to get original Advantage? What is this lice problem? I’ve never heard of or experienced this issue.

  2. stella says:

    I usually put on advantage 20 and my 11lb papillon is find. I could not advantage 20 so I bought advantage 2 and one day after she was looking dazed, not wanting to be walking around, not peeing and pooping like normal. she was not drinking water. I had to force feed the fluids to get her too go. she would hold urine in until she went on blanket. took 4 days for her too be back too normal. the advantage 2 was the only think different I did and this was what happen. I bought 6 month supply and I guess now I will not use it on her and donate the 5 months to animal shelter. let me know is this a side effect.

  3. carol anderson says:

    5 yr. Old Yorkie poo ran around the house for about 45 min. After application of advantage II. Then kept drinking water.after about two hrs.she settled down but still not herself. I followed directions explicitly when I applied product. I am watching her carefully, if not completely herself tomorrow, will take her to vet.

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